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Presbyterian/St. Luke’s Medical Center

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Rocky Mountain Hospital For Children at P/SL

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Osteosarcoma Outcomes

Best Reported Long-Term Survival for Bone Cancer

The intraarterial chemotherapy protocol developed in cooperation with Colorado State University's Animal Cancer Center is utilized at The Denver Clinic for treatment of osteosarcoma and malignant fibroushistiosarcoma of the extremity in children and adults. Patient outcomes following treatment using the I-A protocol by the Denver Clinic physicians have resulted in the best 10-year survival for bone cancer in kids and adults compared to any other center in the world. 

The Denver Clinic physicians have published these outcomes in peer reviewed journals. For more information please feel free to contact The Denver Clinic at 1-800-262-5462.

The articles are available by clicking the links below.

Superior Survival in Treatment of Primary Nonmetastatic Pediatric Osteosarcoma of the Extremity: Wilkins RM, Cullen JC, Odom LF, Jamroz BA, et al; Annals of Surgical Oncology, 2003, 10(5):498-507

Hugate et al. Intraarterial chemotherapy for extremity osteosarcoma and MFH in adults. Clin Orthop Relat Res. 2008 Jun;466(6):1292-301 PMID: 18437502

Cullen et al. The value of serial arteriography in osteosarcoma: delivery of chemotherapy, determination of therapy duration, and prediction of necrosis. J Vasc Interv Radiol. 2005 Aug; 16(8): 1107-19

Wilkins et al. Improved survival in primary nonmetastatic pediatric osteosarcoma of the extremity. Clin Orthop Relat Res. 2005 Sep; 438: 128-36. PMID: 16131881

Intraarterial Chemotherapy for Extremity Osteosarcoma and MFH in Adults: Hugate RR, Wilkins RM, Kelly CM, Hinshaw I, et al: Clinical Orthopedics and Related Research, 2008, 466:1292-1301